Candida albicans ELISA

Candida albicans, an ubiquitously occurring yeast, is the only fungal species belonging to the ‚normal’ microflora of human skin and mucosa. C. albicans is the most prominent causal agent of opportunistic yeastlike infections. Special environmental conditions (elevated pH, reduced bacterial flora, diabetes mellitus, immunosuppression etc.) are required for the infection. The yeast mainly colonising in the intestinal tract spreads to the mucosa during the infectious phases and can cause a systemic candidiasis. These secondary infections occur at the skin, in the mouth, vagina and prostata. Candida albicans can cause a white fungal coat (trush) of the esophagus mucosa in infants, AIDS patienten, seriuosly ill patients and after antibiotic treatment.

The Immunolab Candida albicans IgG/IgM/IgA ELISA kits are quantitative and qualitative tests for the detection of human antibodies to Candida albicans in serum or plasma. Rising IgG antibody titers may reflect invasive candidiasis in immunocompetent patients. Generally, Candida albicans specific IgM antibodies are produced shortly after the infection followed by an increase of specific IgG antibodies. Excessive mucosal infection can lead to a high titer of specific IgA antibodies.

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Features of Immunolab ELISA kits: