Corynebacterium diphtheriae, a gram positive, non spore-forming, immobile rod-shaped bacterium is the causative agent of Diphtheria, a globally spread infectious disease. The infection is transmitted through the aerial-droplet route and rarely by milk or smear infection. After an incubation period of 3-5 days the disease starts with local infections of pharynx and larynx. As complications, long-distance effect damages of the heart, circulation and CNS may occur. The pathogenic effects of the bacteria are caused by an exotoxin. The number of diseases is substantially declined after introduction of a vaccination. Regular vaccinations are still important to check the immune status of adults. A toxoid is used as vaccine which shows the same antigen characteristics as the toxin.
The Immunolab Diphtheria Toxoid IgG ELISA is used for the quantitative detection of IgG antibodies to the Diphtheria toxoid in human serum and plasma. The test should be used to check the immune status before and after a vaccination. The test is standardized by a WHO reference preparation ensuring the comparability of the measured values.
Features of Immunolab ELISA kits: