Echinococcus spp. are 1.4 – 6 mm long tapeworms. The two species E. granulosus (dog tapeworm) and E. multilocularis (fox tapeworm) are principally responsible for human diseases by infecting humans as intermediate hosts. Echinococcosis is a zoonosis caused by the larva of Echinococcus. E. granulosus occurs gloabally, but is quite rare in Germany. E. multilocularis infections are solely limited to the northern hemisphere. Man is infected by ingestion of Echinococcus eggs in case of direct contact to the final hosts (dog, cat, fox) or by ingestion of contaminated fruits and vegetables in case of the fox tapeworm. After hatching in the gut larvae penetrate the intestinal wall and reach other organs by blood circulation. Here they can form big cysts (E. granulosus, cystic hydatidosis) or infiltrative small cysts (E. multilocularis). The disease can progress without any symptoms over years.
The Immunolab Echinococcus IgG ELISA is a quantitative and qualitative test for the detection of human IgG antibodies to Echinococcus in serum and plasma. The origin of the used antigen (E. granulosus or multilocularis) has no relevance for the diagnostics, as the differentiation of the two species is not possible because of the high cross-reactivity using an ELISA detecting antibodies. Apart from diagnostics the test is well suitable as serological control of the therapy.
Features of Immunolab ELISA kits: