Helicobacter pylori, a gram negative, flagellated bacterium, colonizes the mucosas of stomach and small intestine. Helicobacter pylori is known to be the primary cause of chronical active gastritis B and duodenal ulceration since its discovery by Warren and Marshall in 1984. Infection rates in small intestine and stomach ulkus have been found at 93 % and 80 %, respectively. A stomach carcinoma can be developed in case of chronical colonization. One characteristic of Helicobacter is the formation of large Urease quantities. Its enzymatic activity creates an alkaline milieu enabling the survival of the bacterium in the presence of the aggressive stomach acid. H. pylori infection is widespread in industrialized countries. Prevalence increases with each year by 1% so that the contamination level is about 50% among older adults. But not every infection leads to a manifested disease.
The Immunolab Helicobacter pylori IgG/IgM/IgA ELISAs are quantitative and qualitative tests for the detection of human antibodies to H. pylori in serum and plasma. The tests should be performed in case of a reasonable suspicion for an infection with H. pylori or as check of the immune status.
Features of Immunolab ELISA kits: