Influenza viruses are globally the causative agent of influenza (flu). They belong to the family of orthomyxoviruses and can be classified into the genus-specific types A, B und C. Influenza viruses show a high grade of genetic variability which is caused by a high mutation frequency. Specially envelope proteins like hemagglutinin (H) and neuraminidase (N) are subject of variations under immunological pressure causing the antigenic drifts and shifts. These can lead to the typical periodic occurrence of influenza epidemics and pandemics. The acute respiratory disease is caused by Influenza A and B viruses with Influenza A showing the highest pathogenicity. After a short incubation period of 1-5 days a feverish rhinitis and pharyngitis starts. The fever can be very high. Further burdening symptoms are head and bodies aches as well as muscle pain (myositis). Often bacterial superinfections appear which are currently treated with antibiotics. The more seldom infection with Influenza B progresses similar but milder.
The Immunolab Influenza A IgG/IgA/IgB ELISAs are quantitative and qualitative tests for the detection of human antibodies to Influenza A in serum and plasma. The separate detection of the 3 immunoglobulin classes using an ELISA enables a differentiation between acute and previous infection.
Features of Immunolab ELISA kits: