Measles viruses are a subgroup of the paramyxoviruses like mumps, parainfluenza and respiratory syncytial viruses. Measles is a classical childhood disease because of the high contagiosity. The obvious and typical prodromal symptoms appear 10 to 12 days after the infection. The disease is clinically characterized by a distinct rapidly increasing fever, coryza, conjunctivitis, cough and a pathognomomic exanthem (Koplik’s spots). These spots are usually gone by the time the skin rash reaches its peak. The rash of Measles appears after a 3- to 5-days prodrome, some 14 days after exposure. The rash quickly becomes maculopapular and spreads rapidly over the face, neck, trunk and extremities during the next three days. The virus is transmitted by droplet infection from the respiratoty tract of – or direct contact to infected people. The prevalence of measles has declined after the start of vaccination programs.
The Immunolab Measles IgG/IgM/IgA ELISAs are quantitative and qualitative tests for the detection of human antibodies to the Measles virus in serum and plasma. Antibodies can be already detected once the exanthem appears. The separate detection of the 3 immunoglobulin classes using an ELISA enables a differentiation between acute and previous infections.
Features of Immunolab ELISA kits: