Mumps viruses are a subgroup of the paramyxoviruses like measles, parainfluenza and respiratory syncytial viruses. The mumps virus is the causative agent of Parotitis epidemica (mumps). Because of the high contagiosity mumps is a classical childhood disease which frequently occurs during the cold season. Usually children are infected in the age of 4 to 10 years by droplet infection or saliva contact. The incubation period is 12-26 days. Symptoms start with a weak fever for 3-5 days. A characteristic symptom is a painful swelling of the parotid glands. About 25% of the male postpuberal patients suffer from a painful orchitis with a risk of testicle atrophy and sterility. A mild meningoencephalitis is developed in about 10% of the disease cases. A persistent immunity is obtained after passed infection or by vaccination.

The Immunolab Mumps IgG/IgM/IgA ELISAs are quantitative and qualitative tests for the detection of human antibodies to the Mumps virus in serum and plasma. The IgM ELISA is used to detect an acute infection. The separate detection of the 3 immunoglobulin classes using an ELISA enables a differentiation between acute and previous infections.


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